PXD002521

PXD002521 is an original dataset announced via ProteomeXchange.

Title	Analysis of total proteome changes upon long-term treatment with Rho kinase inhibitor H1152.
Description	We quantified protein changes associated with long-term Rho-kinase inhibition, using SILAC proteomics in conjugation with long-termH1152 treatment of mouse embryonic fibroblast cells.
HostingRepository	PRIDE
AnnounceDate	2016-01-18
AnnouncementXML	Submission_2016-01-18_04:58:21.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sandra Kuemper
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	phosphorylated residue
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2015-07-10 09:05:06	ID requested
⏵ 1	2016-01-18 04:58:22	announced

K, ü, mper S, Mardakheh FK, McCarthy A, Yeo M, Stamp GW, Paul A, Worboys J, Sadok A, J, ø, rgensen C, Guichard S, Marshall CJ, Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis. Elife, 5():e12994(2016) [pubmed]

curator keyword: Biological

submitter keyword: Mouse Embryonic Fibroblasts

ROCK1/2

H1152

SILAC

cell cycle

Christopher J Marshall
contact affiliation	Institute of Cancer Research, Division of Cancer Biology, 237 Fulham Road, London SW3 6JB, UK.
contact email	chris.marshall@icr.ac.uk
lab head
Sandra Kuemper
contact affiliation	Institute of Cancer Research
contact email	sandra.kuemper@icr.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/01/PXD002521

PRIDE project URI

• PRIDE
  1. PXD002521
     1. Label: PRIDE project
     2. Name: Analysis of total proteome changes upon long-term treatment with Rho kinase inhibitor H1152.