PXD002300

PXD002300 is an original dataset announced via ProteomeXchange.

Title	Host response to S. pneumoniae TIGR4 and ΔpotABCD
Description	The aim of this experiment is to determine the difference in protein expression, if any, in a mouse model of pneumococcal pneumonia using wild type and a polyamine transport operon deletion mutant strain of S. pneumoniae TIGR4, using expression proteomics. Eight week old female C57bl/6 mice were used in this study. The experimental design had two groups of 3 animals each that were administered 50 µL 1 X 107 CFU wild type S. pneumoniae TIGR4 or S. pneumoniae TIGR4 ΔpotABCD strain by intranasal instillation. The control group with three animals received 50 µL PBS. Mice were euthanized 4 hr and 12 hr post infection and lung tissues were harvested. The control group animals were euthanized 12 hr post infection.
HostingRepository	PRIDE
AnnounceDate	2018-10-27
AnnouncementXML	Submission_2018-10-27_04:30:13.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Joseph Reddy
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2015-06-04 00:45:49	ID requested
⏵ 1	2018-10-27 04:30:15	announced

Rai AN, Thornton JA, Stokes J, Sunesara I, Swiatlo E, Nanduri B, Polyamine transporter in Streptococcus pneumoniae is essential for evading early innate immune responses in pneumococcal pneumonia. Sci Rep, 6():26964(2016) [pubmed]

curator keyword: Biological, Biomedical

submitter keyword: streptococcal pneumonia, mouse, lung

Bindu Nanduri
contact affiliation	Assistant Professor, Dept. of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762
contact email	bindunanduri@gmail.com
lab head
Joseph Reddy
contact affiliation	Basic Sciences, College of Veterinary Medicine
contact email	jsr256@msstate.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/10/PXD002300

PRIDE project URI

• PRIDE
  1. PXD002300
     1. Label: PRIDE project
     2. Name: Host response to S. pneumoniae TIGR4 and ΔpotABCD