PXD002232 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Zebrafish embryo_phosphorylation_18O labeling |
Description | The zebrafish (Danio rerio) is a popular animal model in studies of vertebrate development and organogenesis. Recent research has shown a similarity of approximately 70% between the human and zebrafish genomes and of 84% in human disease-causing genes, specifically. Zebrafish embryos have a number of desirable features, including transparency, a large size, and rapid embryogenesis. Protein phosphorylation is a well-known post-translational modification (PTM), which performs various biological functions. Recent mass spectrometry (MS) developments have enabled the study of global phosphorylation patterns by using MS-based proteomics coupled with TiO2 phosphopeptide enrichment. In the present study, we identified 3,500 non-redundant phosphorylation sites on 2,166 phosphoproteins and 1,564 quantified phosphoproteins in zebrafish embryos. |
HostingRepository | PRIDE |
AnnounceDate | 2015-10-14 |
AnnouncementXML | Submission_2015-10-14_09:41:30.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD002232 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Oh Kwang Kwon |
SpeciesList | scientific name: Danio rerio (Zebrafish) (Brachydanio rerio); NCBI TaxID: 7955; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue; phosphorylated residue; (18)O label at both C-terminal oxygens; O18 label |
Instrument | LTQ Orbitrap Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2015-05-26 03:47:52 | ID requested | |
⏵ 1 | 2015-10-14 09:41:31 | announced | |
Publication List
Kwon OK, Kim SJ, Lee YM, Lee YH, Bae YS, Kim JY, Peng X, Cheng Z, Zhao Y, Lee S, Global analysis of phosphoproteome dynamics in embryonic development of zebrafish (Danio rerio). Proteomics, 16(1):136-49(2016) [pubmed] |
Keyword List
curator keyword: Biological |
submitter keyword: : zebrafish embryo, global phosphoproteome, 18O labeling |
Contact List
Sangkyu Lee |
contact affiliation | College of Pharmacy, Research Institute of Pharmaceutical Sciences, Kyungpook National University |
contact email | sangkyu@knu.ac.kr |
lab head | |
Oh Kwang Kwon |
contact affiliation | Kyungpook National University |
contact email | kok0100@nate.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD002232
- Label: PRIDE project
- Name: Zebrafish embryo_phosphorylation_18O labeling