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PXD002232

PXD002232 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleZebrafish embryo_phosphorylation_18O labeling
DescriptionThe zebrafish (Danio rerio) is a popular animal model in studies of vertebrate development and organogenesis. Recent research has shown a similarity of approximately 70% between the human and zebrafish genomes and of 84% in human disease-causing genes, specifically. Zebrafish embryos have a number of desirable features, including transparency, a large size, and rapid embryogenesis. Protein phosphorylation is a well-known post-translational modification (PTM), which performs various biological functions. Recent mass spectrometry (MS) developments have enabled the study of global phosphorylation patterns by using MS-based proteomics coupled with TiO2 phosphopeptide enrichment. In the present study, we identified 3,500 non-redundant phosphorylation sites on 2,166 phosphoproteins and 1,564 quantified phosphoproteins in zebrafish embryos.
HostingRepositoryPRIDE
AnnounceDate2015-10-14
AnnouncementXMLSubmission_2015-10-14_09:41:30.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD002232
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterOh Kwang Kwon
SpeciesList scientific name: Danio rerio (Zebrafish) (Brachydanio rerio); NCBI TaxID: 7955;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue; phosphorylated residue; (18)O label at both C-terminal oxygens; O18 label
InstrumentLTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02015-05-26 03:47:52ID requested
12015-10-14 09:41:31announced
Publication List
Kwon OK, Kim SJ, Lee YM, Lee YH, Bae YS, Kim JY, Peng X, Cheng Z, Zhao Y, Lee S, Global analysis of phosphoproteome dynamics in embryonic development of zebrafish (Danio rerio). Proteomics, 16(1):136-49(2016) [pubmed]
Keyword List
curator keyword: Biological
submitter keyword: : zebrafish embryo, global phosphoproteome, 18O labeling
Contact List
Sangkyu Lee
contact affiliationCollege of Pharmacy, Research Institute of Pharmaceutical Sciences, Kyungpook National University
contact emailsangkyu@knu.ac.kr
lab head
Oh Kwang Kwon
contact affiliationKyungpook National University
contact emailkok0100@nate.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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