PXD002195

PXD002195 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Fly Stress
Description	Altering the redox state of cysteine residues on protein surfaces is an important response to environmental challenges. While ageing and fasting alter many redox processes, the role of cysteine residues is uncertain. To address this we used a redox proteomic technique, Oxidative Isotope Coded Affinity TAgs (OxICAT), to assess cysteine residue redox changes in Drosophila melanogaster during ageing and fasting. This approach enabled us to simultaneously identify and quantify the redox state of several hundred cysteine residues in vivo.
HostingRepository	PRIDE
AnnounceDate	2018-10-24
AnnouncementXML	Submission_2018-10-24_09:48:25.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Andrew James
SpeciesList	scientific name: Drosophila melanogaster (Fruit fly); NCBI TaxID: 7227;
ModificationList	Applied Biosystems cleavable ICAT(TM) heavy
Instrument	LTQ Orbitrap

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2015-05-19 01:03:49	ID requested
⏵ 1	2018-10-24 09:48:26	announced

Publication List

Menger KE, James AM, Cochem, é HM, Harbour ME, Chouchani ET, Ding S, Fearnley IM, Partridge L, Murphy MP, Fasting, but Not Aging, Dramatically Alters the Redox Status of Cysteine Residues on Proteins in Drosophila melanogaster. Cell Rep, 11(12):1856-65(2015) [pubmed]

Menger KE, James AM, Cochem, é HM, Harbour ME, Chouchani ET, Ding S, Fearnley IM, Partridge L, Murphy MP, Fasting, but Not Aging, Dramatically Alters the Redox Status of Cysteine Residues on Proteins in Drosophila melanogaster. Cell Rep, 11(12):1856-65(2015) [pubmed]

Keyword List

curator keyword: Biological
submitter keyword: Drosophila, ROS, starvation, aging

curator keyword: Biological

submitter keyword: Drosophila, ROS, starvation, aging

Contact List

Michael Patrick Murphy
contact affiliation	MRC Mitochondrial Biology Unit, Cambridge, UK.
contact email	mpm@mrc-mbu.cam.ac.uk
lab head
Andrew James
contact affiliation	MRC
contact email	aj@mrc-mbu.cam.ac.uk
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/10/PXD002195
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/10/PXD002195

PRIDE project URI

Repository Record List

[ + ]