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PXD001974

PXD001974 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteome profiling of human myoblastic RCMH cell line
DescriptionThe study aimed to comprehensively characterize human myoblastic cell line RCMH using using electron microscopic and proteomic approaches. Myoblastic cell lines can be useful to investigate the complex biochemical changes occuring under different conditions that reflect the physiological and pathophysiological mechanisms of muscle. So far, there are no suitable in vitro models of human muscle origin to study a variety of muscle related processes including responses to mechanical stress, EC-coupling and (ER-associated) myopathic disorders. Therefore, we characterized the human immortal myoblastic cell line RCMH and the results suggest RCMH as a suitable in vitro model for investigating human muscle related processes and disorders.
HostingRepositoryPRIDE
AnnounceDate2016-01-26
AnnouncementXMLSubmission_2016-01-26_01:11:33.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD001974
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterLaxmikanth Kollipara
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListOxidation; Carbamidomethyl
InstrumentLTQ Orbitrap Elite
Dataset History
RevisionDatetimeStatusChangeLog Entry
02015-03-25 01:40:24ID requested
12016-01-26 01:11:34announced
Publication List
Kollipara L, Buchkremer S, Weis J, Brauers E, Hoss M, R, ü, tten S, Caviedes P, Zahedi RP, Roos A, Proteome Profiling and Ultrastructural Characterization of the Human RCMH Cell Line: Myoblastic Properties and Suitability for Myopathological Studies. J Proteome Res, 15(3):945-55(2016) [pubmed]
Keyword List
curator keyword: Biological
submitter keyword: RCMH, myoblasts, human cell line, proteome profiling
Contact List
René P. Zahedi
contact affiliationLeibniz-Institut für Analytische Wissenschaften - ISAS - e.V. Otto-Hahn-Str. 6b D-44227 Dortmund Germany Tel.: +49 (0) 231-1392-4143 Fax: +49 (0) 231-1392-4850
contact emailrene.zahedi@isas.de
lab head
Laxmikanth Kollipara
contact affiliationLeibniz – Institut für Analytische Wissenschaften - ISAS - e.V.
contact emaillaxmikanth.kollipara@isas.de
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
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