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PXD001949

PXD001949 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleAP-MS of GFP-MCM2 in the cellular response to etoposide induced DNA damage.
DescriptionSILAC quantitative proteomics using immunoprecipitation of GFP-tagged fusion proteins to identify proteins interacting with the MCM complex, and quantify changes in interactions in response to DNA damage. U2OS cells expressing GFP-MCM2 were used to purify the MCM complex following treatment or not with etoposide, a topoisomerase II inhibitor causing DNA damage.
HostingRepositoryPRIDE
AnnounceDate2017-12-06
AnnouncementXMLSubmission_2017-12-06_09:43:58.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterFrancois-Michel Boisvert
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListubiquitination signature dipeptidyl lysine; phosphorylated residue; monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02015-03-18 04:03:58ID requested
12017-12-06 09:43:59announced
Publication List
Drissi R, Dubois ML, Douziech M, Boisvert FM, Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage. Mol Cell Proteomics, 14(7):2002-13(2015) [pubmed]
Keyword List
curator keyword: Biological, Biomedical
submitter keyword: MCM2, DNA repair, Etoposide
Contact List
Francois-Michel Boisvert
contact affiliationAnatomy and Cell Biology, University of Sherbrooke, Canada
contact emailfm.boisvert@usherbrooke.ca
lab head
Francois-Michel Boisvert
contact affiliationUniversité de Sherbrooke
contact emailfm.boisvert@usherbrooke.ca
dataset submitter
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Dataset FTP location
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PRIDE project URI
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