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PXD001949

DataSet Summary

  • HostingRepository: PRIDE
  • AnnounceDate: 2017-12-06
  • AnnouncementXML: Submission_2017-12-06_09:43:58.xml
  • DigitalObjectIdentifier:
  • ReviewLevel: Peer-reviewed dataset
  • DatasetOrigin: Original data
  • RepositorySupport: Unsupported dataset by repository
  • PrimarySubmitter: Francois-Michel Boisvert
  • Title: AP-MS of GFP-MCM2 in the cellular response to etoposide induced DNA damage.
  • Description: SILAC quantitative proteomics using immunoprecipitation of GFP-tagged fusion proteins to identify proteins interacting with the MCM complex, and quantify changes in interactions in response to DNA damage. U2OS cells expressing GFP-MCM2 were used to purify the MCM complex following treatment or not with etoposide, a topoisomerase II inhibitor causing DNA damage.
  • SpeciesList: scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
  • ModificationList: ubiquitination signature dipeptidyl lysine; phosphorylated residue; monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
  • Instrument: Q Exactive

Dataset History

VersionDatetimeStatusChangeLog Entry
02015-03-18 04:03:58ID requested
12017-12-06 09:43:59announced

Publication List

  1. Drissi R, Dubois ML, Douziech M, Boisvert FM, Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage. Mol Cell Proteomics, 14(7):2002-13(2015) [pubmed]

Keyword List

  1. curator keyword: Biological, Biomedical
  2. submitter keyword: MCM2, DNA repair, Etoposide

Contact List

    Francois-Michel Boisvert
    • contact affiliation: Anatomy and Cell Biology, University of Sherbrooke, Canada
    • contact email: fm.boisvert@usherbrooke.ca
    • lab head:
    Francois-Michel Boisvert
    • contact affiliation: Université de Sherbrooke
    • contact email: fm.boisvert@usherbrooke.ca
    • dataset submitter:

Full Dataset Link List

  1. Dataset FTP location
  2. PRIDE project URI
Repository Record List
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