PXD001949 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | AP-MS of GFP-MCM2 in the cellular response to etoposide induced DNA damage. |
Description | SILAC quantitative proteomics using immunoprecipitation of GFP-tagged fusion proteins to identify proteins interacting with the MCM complex, and quantify changes in interactions in response to DNA damage. U2OS cells expressing GFP-MCM2 were used to purify the MCM complex following treatment or not with etoposide, a topoisomerase II inhibitor causing DNA damage. |
HostingRepository | PRIDE |
AnnounceDate | 2017-12-06 |
AnnouncementXML | Submission_2017-12-06_09:43:58.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Francois-Michel Boisvert |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | ubiquitination signature dipeptidyl lysine; phosphorylated residue; monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2015-03-18 04:03:58 | ID requested | |
⏵ 1 | 2017-12-06 09:43:59 | announced | |
Publication List
Drissi R, Dubois ML, Douziech M, Boisvert FM, Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage. Mol Cell Proteomics, 14(7):2002-13(2015) [pubmed] |
Keyword List
curator keyword: Biological, Biomedical |
submitter keyword: MCM2, DNA repair, Etoposide |
Contact List
Francois-Michel Boisvert |
contact affiliation | Anatomy and Cell Biology, University of Sherbrooke, Canada |
contact email | fm.boisvert@usherbrooke.ca |
lab head | |
Francois-Michel Boisvert |
contact affiliation | Université de Sherbrooke |
contact email | fm.boisvert@usherbrooke.ca |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/12/PXD001949 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD001949
- Label: PRIDE project
- Name: AP-MS of GFP-MCM2 in the cellular response to etoposide induced DNA damage.