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PXD001948

PXD001948 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleAnalysis of pre-and postsynaptic brain receptors, transporters and channels by mass spectrometry
DescriptionAlthough receptors, transporters and channels (RTCs) are key elements in the synaptic membrane, work on analysis and quantification of RTCs by mass spectrometry is limited. Additionally, there is not a single mass spectrometrical study that assigns the localisation of RTCs to the pre- or post-synaptic membrane. Determination of localisation and levels of RTCs in pre- or post-synaptic membranes are essential as RTCs may show different functions in different locations.
HostingRepositoryPRIDE
AnnounceDate2017-10-24
AnnouncementXMLSubmission_2017-10-24_02:17:14.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterFernando Sialana
SpeciesList scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationListTMT6plex-126 reporter+balance reagent acylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentLTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02015-03-18 03:48:17ID requested
12016-12-13 00:52:05announced
22017-10-24 02:17:16announcedUpdated project metadata.
Publication List
Sialana FJ, Gulyassy P, M, á, jek P, Sj, ö, stedt E, Kis V, M, ü, ller AC, Rudashevskaya EL, Mulder J, Bennett KL, Lubec G, Mass spectrometric analysis of synaptosomal membrane preparations for the determination of brain receptors, transporters and channels. Proteomics, 16(22):2911-2920(2016) [pubmed]
Keyword List
curator keyword: Biological
submitter keyword: presynaptic, postsynaptic, membrane, receptors, transporters and channels
Contact List
Gert Lubec
contact affiliationMedical University of Vienna Dept. of Pediatrics Vienna, Austria
contact emailgert.lubec@meduniwien.ac.at
lab head
Fernando Sialana
contact affiliationCeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
contact emailFSialana@cemm.oeaw.ac.at
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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