PXD001904
PXD001904 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Digital mapping of immunopeptidomes: SWATH-MS |
Description | We present a novel mass spectrometry-based high-throughput workflow and an open-source computational and data resource to reproducibly identify and quantify HLA-associated peptides. Collectively, the resources support the generation of HLA allele-specific peptide assay libraries consisting of consensus fragment ion spectra, and the analysis of quantitative digital maps of HLA peptidomes generated by SWATH mass spectrometry (MS) from a range a biological sources. This study represents the first community-based effort to develop a robust platform for the reproducible and quantitative measurement of the entire repertoire of peptides presented by HLA molecules, an essential step towards the design of efficient immunotherapies. |
HostingRepository | PRIDE |
AnnounceDate | 2015-07-14 |
AnnouncementXML | Submission_2015-07-14_04:23:13.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Etienne Caron |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue |
Instrument | TripleTOF 5600 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2015-03-11 06:52:31 | ID requested | |
⏵ 1 | 2015-07-14 04:23:14 | announced |
Publication List
Caron E, Espona L, Kowalewski DJ, Schuster H, Ternette N, Alp, í, zar A, Schittenhelm RB, Ramarathinam SH, Lindestam Arlehamn CS, Chiek Koh C, Gillet LC, Rabsteyn A, Navarro P, Kim S, Lam H, Sturm T, Marcilla M, Sette A, Campbell DS, Deutsch EW, Moritz RL, Purcell AW, Rammensee HG, Stevanovic S, Aebersold R, An open-source computational and data resource to analyze digital maps of immunopeptidomes. Elife, 4():(2015) [pubmed] |
Keyword List
curator keyword: Biomedical, Technical |
submitter keyword: HLA, immunopeptidome, SWATH-MS, DIA |
Contact List
Ruedi Aebersold | |
---|---|
contact affiliation | ETH Zurich Institute of Molecular Systems Biology |
contact email | aebersold@imsb.biol.ethz.ch |
lab head | |
Etienne Caron | |
contact affiliation | ETH Zurich |
contact email | caron@imsb.biol.ethz.ch |
dataset submitter |
Full Dataset Link List
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2015/07/PXD001904 |
PRIDE project URI |
Repository Record List
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