PXD001869

PXD001869 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	iTRAQ-based Subcellular Proteome of Avibirnavirus-infected DF-1 Cells
Description	Infectious bursal disease virus (IBDV) enters the host cells via endocytic pathway to achieve viral replication in the cytoplasm. We performed liquid chromatography-tandem mass spectrometry coupled with isobaric tags for relative and absolute quantification (iTRAQ) labeling of differential abundant protein species of IBDV-infected cells using a subcellular fractionation strategy. We find that viral infection regulates the expression and/or subcellular localization of more than one thousand host proteins in either the nuclear or the cytoplasmic fraction at the early phase of infection. These data provide clues to further understanding the replication and pathogenesis of IBDV and virus-host interactions.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:06:16.569.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yanting Sun
SpeciesList	scientific name: Gallus gallus (Chicken); NCBI TaxID: 9031;
ModificationList	iTRAQ8plex-116 reporter+balance reagent acylated residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2015-03-05 00:18:07	ID requested
1	2020-05-27 02:41:10	announced
⏵ 2	2024-10-22 05:06:17	announced	2024-10-22: Updated project metadata.

Publication List

Sun Y, Hu B, Fan C, Jia L, Zhang Y, Du A, Zheng X, Zhou J, iTRAQ-based quantitative subcellular proteomic analysis of Avibirnavirus-infected cells. Electrophoresis, 36(14):1596-611(2015) [pubmed]
10.1002/elps.201500014;

Sun Y, Hu B, Fan C, Jia L, Zhang Y, Du A, Zheng X, Zhou J, iTRAQ-based quantitative subcellular proteomic analysis of Avibirnavirus-infected cells. Electrophoresis, 36(14):1596-611(2015) [pubmed]

10.1002/elps.201500014;

Keyword List

curator keyword: Biological
submitter keyword: subcellular proteomics, IBDV-infected cells, iTRAQ,Gallus gallus, LC-MS/MS

curator keyword: Biological

submitter keyword: subcellular proteomics, IBDV-infected cells, iTRAQ,Gallus gallus, LC-MS/MS

Contact List

Jiyong Zhou
contact affiliation	Key Laboratory of Animal Virology of Ministry of Agriculture, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, PR China.
contact email	jyzhou@zju.edu.cn
lab head
Yanting Sun
contact affiliation	Key Laboratory of Animal Virology of Ministry of Agriculture, Zhejiang University, Hangzhou 310058, PR China
contact email	yxytsun2101@126.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/05/PXD001869
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/05/PXD001869

PRIDE project URI

Repository Record List

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