PXD001794

PXD001794 is an original dataset announced via ProteomeXchange.

Title	Modulation of Serpin family levels detected by proteomics to monitor colorectal adenoma to carcinoma progression
Description	Colorectal cancer (CRC) remains a major cause of cancer related-death in developed countries. The risk of death is correlated with the stage of CRC determined at the primary diagnosis and early diagnosis is associated with enhanced survival rate. Consequently, there is an interest in using proteomics technologies to identify specific markers of adenomatous polyps as well as advanced stages of CRC.This study supports the concept that serum proteins can discriminate adenoma and CRC patients from unaffected patients and highlights the value of the SERPIN family as potential biomarkers of CRC.
HostingRepository	PRIDE
AnnounceDate	2016-08-26
AnnouncementXML	Submission_2016-08-26_01:11:03.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Luc Camoin
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap; 4800 Proteomics Analyzer

Revision	Datetime	Status	ChangeLog Entry
0	2015-02-09 01:48:06	ID requested
⏵ 1	2016-08-26 01:11:04	announced

Peltier J, Roperch JP, Audebert S, Borg JP, Camoin L, Quantitative proteomic analysis exploring progression of colorectal cancer: Modulation of the serpin family. J Proteomics, 148():139-48(2016) [pubmed]

curator keyword: Biomedical

submitter keyword: Colorectal cancer, iTRAQ, Biomarker, Mass spectrometry, ELISA

Luc Camoin
contact affiliation	Inserm, U1068, CRCM, Marseille Protéomique, Marseille, France
contact email	luc.camoin@inserm.fr
lab head
Luc Camoin
contact affiliation	Life Sciences
contact email	luc.camoin@inserm.fr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/08/PXD001794

PRIDE project URI

• PRIDE
  1. PXD001794
     1. Label: PRIDE project
     2. Name: Modulation of Serpin family levels detected by proteomics to monitor colorectal adenoma to carcinoma progression