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PXD001751

PXD001751 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Human Serum LC-MRM-MS data collected from two cohorts of HCC and cirrhosis patients
Description	In the present study, we used sera from 205 patients representing two cohorts for biomarker discovery using label-free proteomic analysis by liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS). We performed first untargeted proteomic analysis of sera to identify candidate proteins with statistically significant difference between hepatocellular carcinoma (HCC) and patients with liver cirrhosis. These proteins were then evaluated through targeted quantitation by multiple reaction monitoring (MRM) on a triple quadrupole mass spectrometer.
HostingRepository	PeptideAtlas
AnnounceDate	2015-01-29
AnnouncementXML	Submission_2015-01-29_13:04:22.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Habtom Ressom
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	S-carboxamidomethyl-L-cysteine
Instrument	TSQ Vantage

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2015-01-28 15:26:55	ID requested
⏵ 1	2015-01-29 13:04:26	announced

Publication List

no publication

Keyword List

curator keyword: selected reaction monitoring, SRM, targeted

Contact List

Habtom Ressom
contact affiliation	Georgetown University Medical Center
contact email	hwr@georgetown.edu
dataset submitter
Habtom W. Ressom
contact affiliation	Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center
contact email	hwr@georgetown.edu
lab head

Full Dataset Link List

PeptideAtlas dataset URI

PASSEL experiment URI

PASSEL transition group browser URI