PXD001726

PXD001726 is an original dataset announced via ProteomeXchange.

Title	Venom proteomics of Indonesian king cobra
Description	Complementary bottom-up MS/MS analyses contributed to complete a locus-resolved venom phenotype map for O. hannah, the world's longest venomous snake and a species of medical concern across its wide distribution range in forests from India through Southeast Asia. Its venom composition convincingly explains the main neurotoxic effects of human envenoming caused by king cobra bite. The integration of efficient chromatographic separation of the venom components, and locus-resolved toxin identification through top-down and bottom-up MS/MS-based species-specific database searching, promises a bright future to the field of venom research.
HostingRepository	PRIDE
AnnounceDate	2015-08-20
AnnouncementXML	Submission_2015-08-20_01:04:58.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD001726
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Daniel Petras
SpeciesList	scientific name: Ophiophagus hannah (King cobra) (Naja hannah); NCBI TaxID: 8665;
ModificationList	Ammonia-loss: -17.026549; Propionamide: 71.037114; Carbamidomethyl: 57.021464; Acetyl: 42.010565; Glu->pyro-Glu: -18.010565
Instrument	LTQ Orbitrap XL

Revision	Datetime	Status	ChangeLog Entry
0	2015-01-23 06:55:44	ID requested
⏵ 1	2015-08-20 01:04:59	announced

Petras D, Heiss P, S, ü, ssmuth RD, Calvete JJ, Venom Proteomics of Indonesian King Cobra, Ophiophagus hannah: Integrating Top-Down and Bottom-Up Approaches. J Proteome Res, 14(6):2539-56(2015) [pubmed]

curator keyword: Biological

submitter keyword: Snake venomics

Elapidae

King cobra

Ophiophagus hannah

Top-down proteomics

Top-down venomics

Roderich Süssmuth
contact affiliation	TU Berlin
contact email	roderich.suessmuth@tu-berlin.de
lab head
Daniel Petras
contact affiliation	TU Berlin
contact email	daniel.petras@chem.tu-berlin.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2015/08/PXD001726

PRIDE project URI

• PRIDE
  1. PXD001726
     1. Label: PRIDE project
     2. Name: Venom proteomics of Indonesian king cobra