PXD001585

PXD001585 is an original dataset announced via ProteomeXchange.

Title	Phosphodiesterase 9A Controls Nitric-oxide Independent cGMP and Hypertrophic Heart Disease
Description	Rat neonatal cardiac myocytes were treated with PDE5 and PDE9 inhibitor in the presence and absence of L-NAME.
HostingRepository	PRIDE
AnnounceDate	2016-06-24
AnnouncementXML	Submission_2016-06-24_10:41:36.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ronald Holewinski
SpeciesList	scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationList	iodoacetamide derivatized residue; phosphorylated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2014-12-09 01:22:44	ID requested
⏵ 1	2016-06-24 10:41:37	announced

Lee DI, Zhu G, Sasaki T, Cho GS, Hamdani N, Holewinski R, Jo SH, Danner T, Zhang M, Rainer PP, Bedja D, Kirk JA, Ranek MJ, Dostmann WR, Kwon C, Margulies KB, Van Eyk JE, Paulus WJ, Takimoto E, Kass DA, Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease. Nature, 519(7544):472-6(2015) [pubmed]

curator keyword: Biomedical

submitter keyword: cGMP, cyclic GMP, PKG, PDE9, Phosphodiesterase

David A Kass
contact affiliation	The Johns Hopkins University Medical Institutions Department of Medicine, Cardiology Division Baltimore, MD, USA
contact email	dkass@jhmi.edu
lab head
Ronald Holewinski
contact affiliation	Cedar Sinai Medical Center
contact email	ronald.holewinski@cshs.org
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/06/PXD001585

PRIDE project URI

• PRIDE
  1. PXD001585
     1. Label: PRIDE project
     2. Name: Phosphodiesterase 9A Controls Nitric-oxide Independent cGMP and Hypertrophic Heart Disease