PXD001536

PXD001536 is an original dataset announced via ProteomeXchange.

Title	Fast Profiling of Protease Specificity reveals similar substrate specificities for cathepsins K, L and S
Description	N-terminal COFRADIC analysis of cathespine K, L and S to obtain the substrate specificity profile of these cysteine cathepsins.
HostingRepository	PRIDE
AnnounceDate	2015-02-10
AnnouncementXML	Submission_2015-02-10_04:03:54.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD001536
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Emmy Van Quickelberghe
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	L-methionine sulfoxide: 15.994915; 2-pyrrolidone-5-carboxylic acid (Gln): -17.026549; 6x(13)C labeled residue: 6.020129; iodoacetamide derivatized residue: 57.021464; N-acetylated residue: 42.010565; acetate labeling reagent (N-term) (heavy form: +3amu)
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2014-11-25 00:50:39	ID requested
⏵ 1	2015-02-10 04:03:55	announced

Vizovi, š, ek M, Vidmar R, Van Quickelberghe E, Impens F, Andjelkovi, ć U, Soboti, č B, Stoka V, Gevaert K, Turk B, Fonovi, ć M, Fast profiling of protease specificity reveals similar substrate specificities for cathepsins K, L and S. Proteomics, 15(14):2479-90(2015) [pubmed]

curator keyword: Biomedical

submitter keyword: N-terminal COFRADIC, cathespins

Kris Gevaert
contact affiliation	Ghent University Department of Biochemistry B-9000 Ghent Belgium
contact email	kris.gevaert@vib-ugent.be
lab head
Emmy Van Quickelberghe
contact affiliation	Ghent University
contact email	emmy.vanquickelberghe@vib-ugent.be
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2015/02/PXD001536

PRIDE project URI

• PRIDE
  1. PXD001536
     1. Label: PRIDE project
     2. Name: Fast Profiling of Protease Specificity reveals similar substrate specificities for cathepsins K, L and S