This submission is part of the mass spectrometry datasets for the manuscript by St-Denis et al. entitled: Myotubularin-related proteins 3 & 4 interact with PLK1 and CEP55 to control CEP55 recruitment to the midbody and ensure proper abscission. This submission contains 82 RAW files and 82 mgf files, all acquired on a Velos Orbitrap mass spectrometer, as well as results files. See the README file within Methods and Protocols and the accompanying File description.