PXD001398

PXD001398 is an original dataset announced via ProteomeXchange.

Title	Accessibilome of Human Glioblastoma
Description	Functional targeted therapy has unfortunately failed to improve the outcome of glioblastoma patients. Success stories evidenced by the use of antibody-drug conjugates in other tumor types are encouraging, but targets specific to glioblastoma and accessible through the blood stream remain scarce. In the current work we have identified and characterized novel and accessible proteins using an innovative proteomic approach on 6 human glioblastomas. We have also analysed U87 tumors grown of chicken chorioallantoic membrane (CAM) and normal brains from mice as controls. Both were processed in the same fashion as the human tumors.
HostingRepository	PRIDE
AnnounceDate	2014-10-17
AnnouncementXML	Submission_2015-03-16_07:38:42.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Andrei Turtoi
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606; scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Bruker Daltonics esquire series

Revision	Datetime	Status	ChangeLog Entry
0	2014-10-14 08:04:26	ID requested
1	2014-10-17 06:32:54	announced
⏵ 2	2015-03-16 07:38:44	announced	Updated publication reference for PubMed record(s): 25325876.

Turtoi A, Blomme A, Bianchi E, Maris P, Vannozzi R, Naccarato AG, Delvenne P, De Pauw E, Bevilacqua G, Castronovo V, Accessibilome of human glioblastoma: collagen-VI-alpha-1 is a new target and a marker of poor outcome. J Proteome Res, 13(12):5660-9(2014) [pubmed]

curator keyword: Biomedical

submitter keyword: biomarkers

perivascular

targeted therapy;

Vincent Castronovo
contact affiliation	University of Liege GIGA Cancer Metastasis Research Laboratory Liege, Belgium
contact email	vcastronovo@ulg.ac.be
lab head
Andrei Turtoi
contact affiliation	University of Liege, Belgium
contact email	a.turtoi@ulg.ac.be
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2014/10/PXD001398

PRIDE project URI

• PRIDE
  1. PXD001398
     1. Label: PRIDE project
     2. Name: Accessibilome of Human Glioblastoma