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PXD001356

PXD001356 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe zinc repository of Cupriavidus metallidurans
DescriptionZinc is a central player in the metalloproteomes of prokaryotes and eukaryotes. We used a top-down quantitative proteomic approach to reveal the repository of the zinc pools in the proteobacterium Cupriavidus metallidurans. About 60% of the theoretical proteome of C. metallidurans were identified, quantified, and compared between a ΔzupT mutant defect in zinc allocation and its parent strain. In both strains, the number of zinc-binding proteins and their binding sites exceeded that of the zinc ions per cell, indicating that the totality of the zinc proteome provides empty binding sites for incoming zinc ions. This zinc repository plays a central role in zinc homeostasis in C. metallidurans and probably also in other organisms.
HostingRepositoryPRIDE
AnnounceDate2016-05-04
AnnouncementXMLSubmission_2016-05-04_09:00:32.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSacha Baginsky
SpeciesList scientific name: Cupriavidus metallidurans; NCBI TaxID: 119219;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentSynapt MS
Dataset History
RevisionDatetimeStatusChangeLog Entry
02014-09-23 01:50:14ID requested
12016-05-04 09:00:33announced
Publication List
Herzberg M, Dobritzsch D, Helm S, Baginsky S, Nies DH, The zinc repository of Cupriavidus metallidurans. Metallomics, 6(11):2157-65(2014) [pubmed]
Keyword List
curator keyword: Biological
submitter keyword: zinc Cupriavidus
Contact List
Baginsky, Sacha
contact affiliationMartin-Luther-University Halle-Wittenberg, Plant Biochemistry
contact emailsacha.baginsky@biochemtech.uni-halle.de
lab head
Sacha Baginsky
contact affiliationInstitut fuer Biochemie und Biotechnologie
contact emailpflanzen@biochemtech.uni-halle.de
dataset submitter
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Dataset FTP location
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