PXD001278

PXD001278 is an original dataset announced via ProteomeXchange.

Title	Off-target responses in the HeLa proteome subsequent to transient plasmid transfection using SILAC
Description	We report a significant differential expression of proteins, all of which are associated with a viral infection response typified by Interferon type I/II. Notably the upregulated proteins may affect several vital cellular processes, including cell cycle control, translation and post-translational modification of proteins.
HostingRepository	PRIDE
AnnounceDate	2014-12-08
AnnouncementXML	Submission_2014-12-08_04:09:42.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Animesh Sharma
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	6x(13)C labeled residue
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2014-09-02 02:28:11	ID requested
⏵ 1	2014-12-08 04:09:43	announced

Hagen L, Sharma A, Aas PA, Slupphaug G, Off-target responses in the HeLa proteome subsequent to transient plasmid-mediated transfection. Biochim Biophys Acta, 1854(1):84-90(2015) [pubmed]

curator keyword: Biomedical

submitter keyword: SILAC, Off-target, responses, HeLa, proteome , transient , plasmid , transfection

Geir Slupphaug
contact affiliation	Professor Department of Cancer Research and Molecular Medicine Faculty of Medicine Laboratory Centre, 5th floor. Erling Skjalgssons gt. 1 Norwegian University of Science and Technology NTNU 7006 Trondheim, Norway
contact email	geir.slupphaug@ntnu.no
lab head
Animesh Sharma
contact affiliation	Engineer at NTNU, Norway
contact email	sharma.animesh@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2014/12/PXD001278

PRIDE project URI

• PRIDE
  1. PXD001278
     1. Label: PRIDE project
     2. Name: Off-target responses in the HeLa proteome subsequent to transient plasmid transfection using SILAC