PXD001268

PXD001268 is an original dataset announced via ProteomeXchange.

Title	Preterm birth CVF proteomics discovery
Description	Preterm birth, defined as birth <37 weeks of gestation, is a leading cause of infant morbidity and mortality. In the United States, approximately 12% of all births are preterm.1 Despite decades of research, there has been little progress in developing effective interventions to prevent preterm birth. In fact, the rate of preterm birth has increased slightly over the last several decades.2 The ultimate goal of the Genomic and Proteomic Network for Preterm Birth Research (GPN-PBR) is to identify possible biomarkers that could predict the susceptibility to spontaneous preterm birth (SPTB) as well as to shed light on the molecular mechanisms involved in its etiologies. Understanding those mechanisms will help us predict SPTB and may facilitate the introduction of more effective prevention and treatment strategies.
HostingRepository	PRIDE
AnnounceDate	2014-10-23
AnnouncementXML	Submission_2014-10-23_05:00:11.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD001268
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Suhong Zhang
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2014-08-26 07:21:11	ID requested
1	2014-08-28 05:37:13	announced
⏵ 2	2014-10-23 05:00:12	announced	Updated project metadata.

Parry S, Zhang H, Biggio J, Bukowski R, Varner M, Xu Y, Andrews WW, Saade GR, Esplin MS, Leite R, Ilekis J, Reddy UM, Sadovsky Y, Blair IA, Sadovsky Y, Archer SW, Copper RL, Files PB, Harris SL, Baldwin DA, Zimmerle ML, Brandon JL, Jordan S, Jones A, Vorwaller K, Quinn S, Morby VS, Jolley KN, Postma JA, Cheung KH, Losi DelBasso D, Hu B, Huang H, Jin L, Lin AL, Lu CC, Perley L, Simone LJ, Song C, Xiao F, Rouse DJ, Allard D, Wapner R, Divito M, Bousleiman S, Carmona V, Alcon R, Saravia K, Kalemi L, Talucci M, Plante L, Reid Z, Tocci C, Sherwood M, Hoffman M, Lynch S, Bayless A, Benson J, Mann J, Grossman T, Lort S, Vanneman A, Lockhart E, Kitto C, Guzman E, Lake M, Davis S, Falk M, Perez C, Peaceman AM, Stein L, Arego K, Ramos-Brinson M, Mallett G, Thorp JM, Dorman K, Brody S, Blackwell SC, Hutchinson M, Gregg A, Cato P, Clemons T, Ghidini A, Hirsch E, Murray J, Petricoin E, Signore C, Sing CF, Wang X, Maternal serum serpin B7 is associated with early spontaneous preterm birth. Am J Obstet Gynecol, 211(6):678.e1-12(2014) [pubmed]

ProteomeXchange project tag: Human Proteome Project

curator keyword: Biomedical

submitter keyword: HUman CVF LTQ-Obitrap XL

Ian A Blair
contact affiliation	U penn
contact email	ianblair@mail.med.upenn.edu
lab head
Suhong Zhang
contact affiliation	U Penn
contact email	suhongzh@mail.med.upenn.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2014/08/PXD001268

PRIDE project URI

• PRIDE
  1. PXD001268
     1. Label: PRIDE project
     2. Name: Preterm birth CVF proteomics discovery