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PXD001191

PXD001191 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleIntegrative Genomics Positions MKRN1 as a Novel Ribonucleoprotein within the Embryonic Stem Cell Gene Regulatory Network
DescriptionIn this study we affinity purified FLAG-tagged MKRN1 from mouse embryonic stem cells constitutively expressing FLAG:MKRN1 that were pre-treated or untreated with the proteasome inhibitor MG132. FLAG:MKRN1 repeatedly co-immunoprecipitated with 48 proteins irrespective of MG132 treatment. Many of the MKRN1-associated proteins are well-characterized RNA-binding proteins, and post-translational regulators of gene expression.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_04:06:49.502.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterGareth Palidwor
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListmonohydroxylated residue
InstrumentLTQ
Dataset History
RevisionDatetimeStatusChangeLog Entry
02014-07-31 07:51:40ID requested
12018-10-19 00:12:04announced
22024-10-22 04:06:55announced2024-10-22: Updated project metadata.
Publication List
Cassar PA, Carpenedo RL, Samavarchi-Tehrani P, Olsen JB, Park CJ, Chang WY, Chen Z, Choey C, Delaney S, Guo H, Guo H, Tanner RM, Perkins TJ, Tenenbaum SA, Emili A, Wrana JL, Gibbings D, Stanford WL, Integrative genomics positions MKRN1 as a novel ribonucleoprotein within the embryonic stem cell gene regulatory network. EMBO Rep, 16(10):1334-57(2015) [pubmed]
10.15252/embr.201540974;
Keyword List
curator keyword: Biological
submitter keyword: Embryonic Stem Cells / Makorin-1 / RNA metabolism / stress granules
Contact List
Dr. William Stanford
contact affiliationOttawa Hospital Research Institute
contact emailwstanford@ohri.ca
lab head
Gareth Palidwor
contact affiliationOttawa Hospital Research Institute
contact emailgpalidwor@Ohri.ca
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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