PXD001191 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Integrative Genomics Positions MKRN1 as a Novel Ribonucleoprotein within the Embryonic Stem Cell Gene Regulatory Network |
Description | In this study we affinity purified FLAG-tagged MKRN1 from mouse embryonic stem cells constitutively expressing FLAG:MKRN1 that were pre-treated or untreated with the proteasome inhibitor MG132. FLAG:MKRN1 repeatedly co-immunoprecipitated with 48 proteins irrespective of MG132 treatment. Many of the MKRN1-associated proteins are well-characterized RNA-binding proteins, and post-translational regulators of gene expression. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_04:06:49.502.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Gareth Palidwor |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | monohydroxylated residue |
Instrument | LTQ |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2014-07-31 07:51:40 | ID requested | |
1 | 2018-10-19 00:12:04 | announced | |
⏵ 2 | 2024-10-22 04:06:55 | announced | 2024-10-22: Updated project metadata. |
Publication List
Cassar PA, Carpenedo RL, Samavarchi-Tehrani P, Olsen JB, Park CJ, Chang WY, Chen Z, Choey C, Delaney S, Guo H, Guo H, Tanner RM, Perkins TJ, Tenenbaum SA, Emili A, Wrana JL, Gibbings D, Stanford WL, Integrative genomics positions MKRN1 as a novel ribonucleoprotein within the embryonic stem cell gene regulatory network. EMBO Rep, 16(10):1334-57(2015) [pubmed] |
10.15252/embr.201540974; |
Keyword List
curator keyword: Biological |
submitter keyword: Embryonic Stem Cells / Makorin-1 / RNA metabolism / stress granules |
Contact List
Dr. William Stanford |
contact affiliation | Ottawa Hospital Research Institute |
contact email | wstanford@ohri.ca |
lab head | |
Gareth Palidwor |
contact affiliation | Ottawa Hospital Research Institute |
contact email | gpalidwor@Ohri.ca |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/10/PXD001191 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD001191
- Label: PRIDE project
- Name: Integrative Genomics Positions MKRN1 as a Novel Ribonucleoprotein within the Embryonic Stem Cell Gene Regulatory Network