PXD001112

PXD001112 is an original dataset announced via ProteomeXchange.

Title	Comparative proteomics analysis reveals the adaptation strategies of the alpine plant Potentilla saundersiana along the altitude gradient of the Northwestern Tibetan Plateau
Description	The altitude gradient limits the growth and distribution of alpine plants.Alpine plants have developed strategies to survive the extremely cold conditions prevailing at high altitudes; however, the mechanism underlying the evolution of these strategies remains unknown. The alpine plant Potentilla saundersiana is widespread in the Northwestern Tibetan Plateau. In this study, we conducted a comparative proteomics analysis to investigate the dynamic patterns of protein expression of P. saundersiana located at five different altitudes. We detected and functionally characterized 118 differentially expressed proteins. Our study confirmed that increasing levels of antioxidant proteins, and their respective activities, and accumulation of primary metabolites, such as proline and sugar, confer tolerance to the alpine environment in P. saundersiana. Proteins species associated with the epigenetic regulation of DNA stability and post-translational protein degradation were also involved in this process. Furthermore, our results showed that P. saundersiana modulated the root architecture and leaf phenotype to enhance adaptation to alpine environmental stress through mechanisms that involved hormone synthesis and signal transduction, particularly the cross-talk between auxin and strictosidine. Based on these findings, we conclude that P. saundersiana uses multiple strategies to adapt to the high-altitude environment of the Northwestern Tibetan Plateau.
HostingRepository	PRIDE
AnnounceDate	2022-02-22
AnnouncementXML	Submission_2022-02-22_03:41:15.236.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD001112
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Xiangyang Hu
SpeciesList	scientific name: Potentilla saundersiana; NCBI TaxID: 667282;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2014-07-08 02:16:24	ID requested
⏵ 1	2022-02-22 03:41:16	announced

Ma L, Sun X, Kong X, Galvan JV, Li X, Yang S, Yang Y, Yang Y, Hu X, Physiological, biochemical and proteomics analysis reveals the adaptation strategies of the alpine plant Potentilla saundersiana at altitude gradient of the Northwestern Tibetan Plateau. J Proteomics, 112():63-82(2015) [pubmed]

curator keyword: Biological

submitter keyword: Comparative proteomics

Potentilla saundersiana

adaptation;

Xiangyang Hu
contact affiliation	Chinese Academy of Sciences
contact email	huxiangyang@mail.kib.ac.cn
lab head
Xiangyang Hu
contact affiliation	Chinese Academy of Sciences
contact email	huxiangyang@mail.kib.ac.cn
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD001112
     1. Label: PRIDE project
     2. Name: Comparative proteomics analysis reveals the adaptation strategies of the alpine plant Potentilla saundersiana along the altitude gradient of the Northwestern Tibetan Plateau