PXD001003

PXD001003 is an original dataset announced via ProteomeXchange.

Title	Comparative analysis of the adaptation of Staphylococcus aureus to internalization by different types of human non-professional phagocytic host cells
Description	We comparatively analyzed survival and physiological adaptation of S. aureus HG001 to two human lung epithelial cell lines (S9 and A549), and human embryonic kidney cells (HEK 293). Combining enrichment of bacteria from host-pathogen assays by cell sorting and quantitation of the pathogen´s proteome by mass spectrometry we characterized S. aureus adaptation during the initial phase between 2.5 h and 6.5 h post-infection.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:09:02.308.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Maren Depke
SpeciesList	scientific name: Staphylococcus aureus; NCBI TaxID: 1280;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2014-05-23 07:08:35	ID requested
1	2014-09-01 05:47:29	announced
2	2014-10-22 07:19:53	announced	Updated project metadata.
3	2014-10-22 08:30:05	announced	Updated project metadata.
⏵ 4	2024-10-22 04:09:04	announced	2024-10-22: Updated project metadata.

Surmann K, Michalik S, Hildebrandt P, Gierok P, Depke M, Brinkmann L, Bernhardt J, Salazar MG, Sun Z, Shteynberg D, Kusebauch U, Moritz RL, Wollscheid B, Lalk M, V, ö, lker U, Schmidt F, Comparative proteome analysis reveals conserved and specific adaptation patterns of Staphylococcus aureus after internalization by different types of human non-professional phagocytic host cells. Front Microbiol, 5():392(2014) [pubmed]

10.3389/fmicb.2014.00392;

curator keyword: Biomedical

submitter keyword: cell culture infection model, bacterial adaptation to internalization in host cells, Q Exactive,Staphylococcus aureus HG001

Frank Schmidt
contact affiliation	University Medicine Greifswald Interfaculty Institute for Genetics and Functional Genomics Department of Functional Genomics ZIK-FunGene Junior Research Group Applied Proteomics Friedrich-Ludwig-Jahn-Str. 15a D-17487 Greifswald Germany Phone: +49-3834-865887 Fax: +49-3834-86795887
contact email	frank.schmidt@uni-greifswald.de
lab head
Maren Depke
contact affiliation	Department of Functional Genomics
contact email	depke@uni-greifswald.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2014/09/PXD001003

PRIDE project URI

• PRIDE
  1. PXD001003
     1. Label: PRIDE project
     2. Name: Comparative analysis of the adaptation of Staphylococcus aureus to internalization by different types of human non-professional phagocytic host cells