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PXD000991

PXD000991 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMethod to identify novel proteoform peptides from salivary supernatant.
DescriptionWe describe the use Galaxy framework to facilitate complete proteogenomic analysis for a representative salivary dataset. We demonstrate how Galaxy’s many features make it a unique and ideal solution for proteogenomic analysis. We highlight Galaxy’s flexibility by creating a modular workflow incorporating both established and customized software and processing steps that improve depth and quality of proteogenomic results. We demonstrate Galaxy’s accessibility, via the easy sharing of complete, and even complex (approximately 140 steps), proteogenomic workflows, which can be used and customized by others via a public instance of the framework (usegalaxyp.org). Our results provide a blueprint for the establishment of the Galaxy framework as an ideal solution for the emerging field of proteogenomics.
HostingRepositoryPRIDE
AnnounceDate2015-01-05
AnnouncementXMLSubmission_2015-01-05_07:28:33.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterPratik Jagtap
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue
InstrumentLTQ Orbitrap
Dataset History
RevisionDatetimeStatusChangeLog Entry
02014-05-20 08:14:00ID requested
12015-01-05 07:28:34announced
Publication List
Jagtap PD, Johnson JE, Onsongo G, Sadler FW, Murray K, Wang Y, Shenykman GM, Bandhakavi S, Smith LM, Griffin TJ, Flexible and accessible workflows for improved proteogenomic analysis using the Galaxy framework. J Proteome Res, 13(12):5898-908(2014) [pubmed]
Keyword List
curator keyword: Technical
submitter keyword: Saliva, proteoforms, proteogenomics
Contact List
Timothy Griffin
contact affiliationDepartment of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, USA
contact emailtgriffin@umn.edu
lab head
Pratik Jagtap
contact affiliationCenter for Mass Spectrometry and Proteomics
contact emailpjagtap@umn.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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