PXD000972

PXD000972 is an original dataset announced via ProteomeXchange.

Title	Phosphoproteomic analysis of TCR signaling with inhibitors
Description	MAPK-Erk and calcium-Calcineurin pathways are major signaling pathways activated during TCR signal transduction. We investigated the effect of these signaling pathway with the use of selective inhibitors of Mek and calcineurin.
HostingRepository	PRIDE
AnnounceDate	2022-02-22
AnnouncementXML	Submission_2022-02-22_03:45:32.840.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD000972
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Atsushi Hatano
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	Phospho; iTRAQ4plex; Glu->pyro-Glu; Oxidation; Carbamidomethyl; Gln->pyro-Glu
Instrument	QSTAR

Revision	Datetime	Status	ChangeLog Entry
0	2014-05-14 08:13:49	ID requested
⏵ 1	2022-02-22 03:45:33	announced

Hatano A, Matsumoto M, Nakayama KI, Phosphoproteomics analyses show subnetwork systems in T-cell receptor signaling. Genes Cells, 21(10):1095-1112(2016) [pubmed]

curator keyword: Biomedical

submitter keyword: TCR signaling, MEK inhibitor, Calcineurin inhibitor

Keiichi I. Nakayama
contact affiliation	Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University
contact email	nakayak1@bioreg.kyushu-u.ac.jp
lab head
Atsushi Hatano
contact affiliation	Medical Institute of Bioregulation, Kyushu University
contact email	atsushi_hatano@bioreg.kyushu-u.ac.jp
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD000972

PRIDE project URI

• PRIDE
  1. PXD000972
     1. Label: PRIDE project
     2. Name: Phosphoproteomic analysis of TCR signaling with inhibitors