PXD000971

PXD000971 is an original dataset announced via ProteomeXchange.

Title	Proteomic Analysis of Livers from Fat-fed Mice Deficient in Either PKCδ or PKCɛ
Description	To investigate the mechanisms of lipid-activated protein kinase C (PKC) family, PKCδ or PKCɛ, involved in insulin resistance and fatty acid metabolism, we employed an in vivo adaptation of SILAC to examine the effects of a fat diet together with deletion of PKCδ or PKCɛ on the expression of liver proteins.
HostingRepository	PRIDE
AnnounceDate	2014-11-04
AnnouncementXML	Submission_2014-11-04_04:02:47.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Bing Qing Liao
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2014-05-14 02:41:24	ID requested
⏵ 1	2014-11-04 04:02:48	announced

Liao BM, Raddatz K, Zhong L, Parker BL, Raftery MJ, Schmitz-Peiffer C, identifies Htatip2 as a regulator of lipid metabolism. Proteomics, 14(21-22):2578-87(2014) [pubmed]

curator keyword: Biomedical

submitter keyword: mouse, protein kinase C, SILAC, liver, fatty acid metabolism, high-fat diet, glucose intolerance, insulin resistance

Carsten Schmitz-Peiffer
contact affiliation	Diabetes and Obesity Program, Garvan Institute of Medical Research, Australia
contact email	c.schmitz-peiffer@unsw.edu.au
lab head
Bing Qing Liao
contact affiliation	Garvan Institute of Medical Research
contact email	m.liao@garvan.org.au
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2014/11/PXD000971

PRIDE project URI

• PRIDE
  1. PXD000971
     1. Label: PRIDE project
     2. Name: Proteomic Analysis of Livers from Fat-fed Mice Deficient in Either PKCδ or PKCɛ