PXD000932

PXD000932 is an original dataset announced via ProteomeXchange.

Title	The Haemophilus ducreyi LspA1 Protein Inhibits Phagocytosis By Using a New Mechanism Involving Activation of C-Terminal Src Kinase
Description	LspA virulance factors of H. ducreyi inhibit phagocytosis by activating C-terminal Src kinase. This SILAC analysis identified Src kinase as the predominant mamallian protein interacting with the YL2 domain of LspA1.
HostingRepository	PRIDE
AnnounceDate	2014-10-23
AnnouncementXML	Submission_2014-10-23_03:38:34.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	David Trudgian
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2014-04-25 05:24:31	ID requested
1	2014-04-29 03:03:43	announced
2	2014-07-24 05:17:37	announced	Updated project metadata.
3	2014-08-08 06:04:11	announced	Updated project metadata.
⏵ 4	2014-10-23 03:38:35	announced	Updated project metadata.

Dodd DA, Worth RG, Rosen MK, Grinstein S, van Oers NS, Hansen EJ, The Haemophilus ducreyi LspA1 protein inhibits phagocytosis by using a new mechanism involving activation of C-terminal Src kinase. mBio, 5(3):e01178-14(2014) [pubmed]

curator keyword: Biomedical

submitter keyword: Src kinase, activation, SILAC

Eric Hansen
contact affiliation	Department of Microbiology, The University of Texas Southwestern Medical School, Dallas, Texas, USA.
contact email	eric.hansen@utsouthwestern.edu
lab head
David Trudgian
contact affiliation	Ex-UTSW & Oxford
contact email	dave@trudgian.net
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2014/04/PXD000932

PRIDE project URI

• PRIDE
  1. PXD000932
     1. Label: PRIDE project
     2. Name: The Haemophilus ducreyi LspA1 Protein Inhibits Phagocytosis By Using a New Mechanism Involving Activation of C-Terminal Src Kinase