PXD000921

PXD000921 is an original dataset announced via ProteomeXchange.

Title	Analysis of low molecular weight protein profile in whole saliva with special reference to ovulation
Description	Whole saliva is contains major, minor and gingival crevicular fluid/secretions and it plays vital role in maintaining the oral health, three pair of major salivary glands consist of parotid, submandibular and sub-lingual glands. Saliva is a good biological fluid to explore health and disease status of human. Further, the saliva secrets from major salivary glands and have various biomolecules such as, proteins, enzymes and ions originated from serum and saliva is easily accessible through a safe and noninvasive method. In contrast, the concentrations of biomolecules in saliva are generally one tenth to one thousand of the levels in blood. Ovulation is an exclusive process through the mature (pre-ovulatory) ovarian follicles reacts to the surge of luteinizing hormone (LH) and burst to discharge fertilizable oocytes. The LH surge initiates a flow of proteolytic actions with the aim of control ovulation. Presently, many salivary proteins are have been showed as a biomarker such as Sjogren’s syndrome, Lung cancer, oral and Systemic diseases, HIV-seropositive patients, dental pellicle development, and hyperglycemia. However, there is no prominent marker protein was reported for monitoring ovulation process in human saliva. It is important prediction of fertile period in women for various applications like assisted reproduction and invitro fertilization.
HostingRepository	PRIDE
AnnounceDate	2017-10-24
AnnouncementXML	Submission_2017-10-24_03:21:53.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD000921
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Saibaba Ganesan
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	Oxidation; Carbamidomethyl
Instrument	ultraflex

Revision	Datetime	Status	ChangeLog Entry
0	2014-04-23 02:17:47	ID requested
1	2017-01-03 03:14:12	announced
⏵ 2	2017-10-24 03:21:54	announced	Updated project metadata.

Saibaba G, Rajesh D, Muthukumar S, Sathiyanarayanan G, Padmanabhan P, Akbarsha MA, Guly, á, s B, Archunan G, Proteomic analysis of human saliva: An approach to find the marker protein for ovulation. Reprod Biol, 16(4):287-294(2016) [pubmed]

curator keyword: Biomedical

submitter keyword: saliva, protein, ovulation, LC-MSMS, cystatin

Archunan Govindaraju
contact affiliation	Centre for Pheromone Technology, Department of Animal Science, Bharathidasan University, Tiruchirappalli - 620024, Tamilnadu, India.
contact email	garchu56@yahoo.co.in
lab head
Saibaba Ganesan
contact affiliation	Bharathidasan University
contact email	saibabag@bdu.ac.in
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD000921
     1. Label: PRIDE project
     2. Name: Analysis of low molecular weight protein profile in whole saliva with special reference to ovulation