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PXD000830

PXD000830 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	MRM qualification of plasma/serum protein biomarkers for progression from MTB infection to disease
Description	The overall scope of this study is to find early tuberculosis (TB) candidate protein biomarkers in different TB study groups vs. controls. The identified biomarkers may become the basis of a rapid diagnostic test able to identify active TB earlier than current practice. In addition, the candidate biomarkers may predict which patients are likely to convert from latent infection to active disease. . This project uses plasma and serum samples collected in a long-standing TB household contact study, the Kawempe Community Health Study, conducted in Kampala, Uganda, a TB endemic area. The study utilizes samples from TB index cases and household contacts that were negative for TB at recruitment. A subset of these contacts developed Mtb infection (i.e., their Tuberculin Skin Test (TST) converted to positive) after 3-6 months, and smaller subset developed active TB after 3 months of follow-up. Control patients were still TST negative at 12 months or 24 months of follow-up. This dataset corresponds to the qualification phase of the study.
HostingRepository	PeptideAtlas
AnnounceDate	2014-03-18
AnnouncementXML	Submission_2014-03-18_09:55:48.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Eustache Paramithiotis
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	QTRAP 5500

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2014-03-14 12:27:02	ID requested
⏵ 1	2014-03-18 09:55:49	announced

Publication List

no publication

Keyword List

curator keyword: selected reaction monitoring, SRM, targeted

Contact List

Eustache Paramithiotis
contact affiliation
contact email	eparamithiotis@caprion.com
dataset submitter
Eustache Paramithiotis
contact affiliation	Caprion.com
contact email	eparamithiotis@caprion.com
lab head

Full Dataset Link List

PeptideAtlas dataset URI

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