PXD000795 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Identification of full length Hsp90 from Giardia lamblia cell lysate |
Description | In the present study using mass-spectrometry we identify the sequence of the unique, junctional peptide contributed by the 5’ UTR of HspC ORF in the full length Hsp90 from Giardia lamblia. This peptide is critical for the catalytic function of Hsp90 as it harbours an essential “Arg” homolog in its sequence. We also show that full length GlHsp90 possesses all the functional hall marks of a canonical Hsp90 including its ability to bind and hydrolyze ATP. |
HostingRepository | PRIDE |
AnnounceDate | 2016-07-09 |
AnnouncementXML | Submission_2016-07-08_19:23:23.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Utpal Tatu |
SpeciesList | scientific name: Giardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia lamblia); NCBI TaxID: 184922; |
ModificationList | iodoacetamide derivatized residue |
Instrument | QSTAR |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2014-03-05 03:02:03 | ID requested | |
⏵ 1 | 2016-07-08 19:23:24 | announced | |
Publication List
Nageshan RK, Roy N, Ranade S, Tatu U, Trans-spliced heat shock protein 90 modulates encystation in Giardia lamblia. PLoS Negl Trop Dis, 8(5):e2829(2014) [pubmed] |
Keyword List
submitter keyword: Hsp90, Giardia lamblia, trans-splicing, junctional peptide, molecular chaperones, ATPase activity |
Contact List
Prof. Utpal Tatu |
contact affiliation | Department of Biochemistry, Indian Institute of Science, Bangalore - 560 012 India |
contact email | tatu@biochem.iisc.ernet.in |
lab head | |
Utpal Tatu |
contact affiliation | Dept. of Biochemistry, Indian Institute of Science, Bangalore, India |
contact email | tatu@biochem.iisc.ernet.in |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/07/PXD000795 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD000795
- Label: PRIDE project
- Name: Identification of full length Hsp90 from Giardia lamblia cell lysate