PXD000740

PXD000740 is an original dataset announced via ProteomeXchange.

Title	Synovial fluid proteome in rheumatoid arthritis
Description	Rheumatoid arthritis (RA) is a chronic autoinflammatory disorder that affects small joints. Despite intense efforts, there isno definitive marker yet for early diagnosis RA and for monitoring the progression of this disease. We sought to catalog the proteins present in the synovial fluid of patients with rheumatoid arthritis. To identify lower abundance proteins, we undertook two approaches – we depleted the abundant proteins using a multiple affinity removal system (MARS14) column and we enriched glycoproteins using a lectin affinity column. The peptides were analyzed by LC-MS/MS on a high resolution Fourier transform mass spectrometer.
HostingRepository	PRIDE
AnnounceDate	2016-06-13
AnnouncementXML	Submission_2016-06-13_01:25:06.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Akhilesh Pandey
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; acetylated residue; deamidated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap XL ETD

Revision	Datetime	Status	ChangeLog Entry
0	2014-02-05 01:21:28	ID requested
⏵ 1	2016-06-13 01:25:10	announced

Bhattacharjee M, Balakrishnan L, Renuse S, Advani J, Goel R, Sathe G, Keshava Prasad TS, Nair B, Jois R, Shankar S, Pandey A, Synovial fluid proteome in rheumatoid arthritis. Clin Proteomics, 13():12(2016) [pubmed]

submitter keyword: Synovial fluid, Rheumatoid arthritis

Akhilesh Pandey
contact affiliation	McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
contact email	pandey@jhmi.edu
lab head
Akhilesh Pandey
contact affiliation	Institute of Genetic Medicine
contact email	pandey@jhmi.edu
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD000740
     1. Label: PRIDE project
     2. Name: Synovial fluid proteome in rheumatoid arthritis