PXD000724

PXD000724 is an original dataset announced via ProteomeXchange.

Title	Proteomic analysis of glycosomes from Leishmania donovani
Description	Leishmania donovani is a kinetoplastid protozoan which causes Kala-azar or visceral leishmaniasis.Leishmania possess glycosomes that are unique and specialized subcellular microbody organelles. Glycosomes are known to harbor most peroxisomal enzymes and in addition they also possess glycolytic enzymes. In the present study, we carried out proteomic profiling of purified glycosomes isolated from L. donovani promastigotes using high resolution mass spectrometry. The majority of identified proteins are involved in metabolic processes such as carbohydrate, lipid and nucleic acid metabolism. Our present proteomic analysis is the most comprehensive study till date to map the proteome of L. donovaniglycosomes.
HostingRepository	PRIDE
AnnounceDate	2015-03-27
AnnouncementXML	Submission_2015-03-27_01:30:45.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Akhilesh Pandey
SpeciesList	scientific name: Leishmania donovani; NCBI TaxID: 5661;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2014-01-31 01:47:29	ID requested
1	2015-03-25 03:09:20	announced
⏵ 2	2015-03-27 01:30:47	announced	Updated project metadata.

Jamdhade MD, Pawar H, Chavan S, Sathe G, Umasankar PK, Mahale KN, Dixit T, Madugundu AK, Prasad TS, Gowda H, Pandey A, Patole MS, Comprehensive proteomics analysis of glycosomes from Leishmania donovani. OMICS, 19(3):157-70(2015) [pubmed]

curator keyword: Biological

submitter keyword: Subcellular organelle, kinetoplastid, leishmaniasis

AKHILESH PANDEY
contact affiliation	McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore MD 21205
contact email	pandey@jhmi.edu
lab head
Akhilesh Pandey
contact affiliation	Johns Hopkins University
contact email	pandey@jhmi.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2015/03/PXD000724

PRIDE project URI

• PRIDE
  1. PXD000724
     1. Label: PRIDE project
     2. Name: Proteomic analysis of glycosomes from Leishmania donovani