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PXD000701

PXD000701 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePhosphoproteome of ecto-ATP synthase blockade in tumor xenograft tissues
DescriptionATP synthase is crucial for ATP synthesis in living cells. Recently, ATP synthase was found not only in mitochondria but also on the extracellular surface, named as ectopic ATP synthase (ecto-ATP synthase). ATP synthase inhibitor is a potential drug candidate to fight cancer by blocking the ecto-ATP synthase of cells. In this study, we applied dynamic phosphoproteomics to elucidate the molecular responses to ecto-ATP synthase blockade.
HostingRepositoryPRIDE
AnnounceDate2015-11-06
AnnouncementXMLSubmission_2015-11-06_07:26:13.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD000701
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterChia-Wei Hu
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; 2x(13)C: 4x(2)H labeled dimethylated residue; iodoacetamide derivatized residue; phosphorylated residue; formylated residue
InstrumentTripleTOF 5600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02014-01-21 06:30:26ID requested
12015-11-06 07:26:14announced
Publication List
Hu CW, Hsu CL, Wang YC, Ishihama Y, Ku WC, Huang HC, Juan HF, Temporal Phosphoproteome Dynamics Induced by an ATP Synthase Inhibitor Citreoviridin. Mol Cell Proteomics, 14(12):3284-98(2015) [pubmed]
Keyword List
submitter keyword: Phosphoproteome, ecto-ATP synthase, tumor xenograft
Contact List
Hsueh-Fen Juan
contact affiliationSystems Biology Lab, Department of Life Science, National Taiwan University, Taiwan
contact emailyukijuan@ntu.edu.tw
lab head
Chia-Wei Hu
contact affiliationInstitute of molecular and cellular biology
contact emailhkmq8195@gmail.com
dataset submitter
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Dataset FTP location
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