PXD000696 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Quantitative phosphoproteome of ecto-ATP synthase blockade in lung cancer cells |
Description | ATP synthase is crucial for ATP synthesis in living cells. Recently, ATP synthase was found not only in mitochondria but also on the extracellular surface, named as ectopic ATP synthase (ecto-ATP synthase). ATP synthase inhibitor is a potential drug candidate to fight cancer by blocking the ecto-ATP synthase of cancer cells. In this study, we applied dynamic phosphoproteomics to elucidate the molecular responses to ecto-ATP synthase blockade. |
HostingRepository | PRIDE |
AnnounceDate | 2015-11-06 |
AnnouncementXML | Submission_2015-11-06_04:46:02.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Chia-Wei Hu |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; 2x(13)C: 4x(2)H labeled dimethylated residue; iodoacetamide derivatized residue; phosphorylated residue; dimethylated residue |
Instrument | LTQ Orbitrap |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2014-01-21 01:36:56 | ID requested | |
⏵ 1 | 2015-11-06 04:46:03 | announced | |
Publication List
Hu CW, Hsu CL, Wang YC, Ishihama Y, Ku WC, Huang HC, Juan HF, Temporal Phosphoproteome Dynamics Induced by an ATP Synthase Inhibitor Citreoviridin. Mol Cell Proteomics, 14(12):3284-98(2015) [pubmed] |
Keyword List
submitter keyword: Phosphoproteome, ecto-ATP synthase, lung cancer cells |
Contact List
Hsueh-Fen Juan |
contact affiliation | System biology lab, Department of life science, National Taiwan University, Taiwan |
contact email | yukijuan@ntu.edu.tw |
lab head | |
Chia-Wei Hu |
contact affiliation | Institute of molecular and cellular biology |
contact email | hkmq8195@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD000696
- Label: PRIDE project
- Name: Quantitative phosphoproteome of ecto-ATP synthase blockade in lung cancer cells