PXD000683

PXD000683 is an original dataset announced via ProteomeXchange.

Title	Genomics and Proteomics Provide New Insight into the Commensal and Pathogenic Lifestyles of Bovine and Human-associated Staphylococcus epidermidis
Description	The goal of the present study is to understand mechanisms by which SE can infect the bovine host and persist in the mammary gland. For this purpose we determined the whole genome and four plasmid sequences of the SE strain PM221 originating from spontaneous persistent bovine IMI. We compared the genomic data with those of ATCC12228 and RP62A to screen for conserved and acquired gene pools. To confirm and complement these findings two-dimensional difference gel electrophoresis (2D DIGE) involving each three strains, surfome shaving and experimental infections in a bovine model was applied to indicate potential differences.
HostingRepository	PRIDE
AnnounceDate	2014-07-24
AnnouncementXML	Submission_2014-07-24_03:49:19.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Pia Siljamäki
SpeciesList	scientific name: Staphylococcus epidermidis; NCBI TaxID: 1282;
ModificationList	No PTMs are included in the dataset
Instrument	QSTAR

Revision	Datetime	Status	ChangeLog Entry
0	2014-01-14 03:23:44	ID requested
1	2014-07-15 02:24:23	announced
⏵ 2	2014-07-24 03:49:19	announced	Updated project metadata.

Savijoki K, Iivanainen A, Siljam, ä, ki P, Laine PK, Paulin L, Karonen T, Py, ö, r, ä, l, ä S, Kankainen M, Nyman TA, Salom, ä, ki T, Koskinen P, Holm L, Simojoki H, Taponen S, Sukura A, Kalkkinen N, Auvinen P, Varmanen P, Genomics and Proteomics Provide New Insight into the Commensal and Pathogenic Lifestyles of Bovine- and Human-Associated Staphylococcus epidermidis Strains. J Proteome Res, 13(8):3748-3762(2014) [pubmed]

curator keyword: Biomedical, Biological

submitter keyword: Staphylococcus epidermidis, genome, proteome, IMI, pathogenicity

Tuula A Nyman
contact affiliation	Institute of Biotechnology, Proteomics Unit, University of Helsinki, Finland
contact email	tuula.nyman@helsinki.fi
lab head
Pia Siljamäki
contact affiliation	Institute of Biotechnology
contact email	pia.siljamaki@helsinki.fi
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2014/07/PXD000683

PRIDE project URI

• PRIDE
  1. PXD000683
     1. Label: PRIDE project
     2. Name: Genomics and Proteomics Provide New Insight into the Commensal and Pathogenic Lifestyles of Bovine and Human-associated Staphylococcus epidermidis