PXD000517

PXD000517 is an original dataset announced via ProteomeXchange.

Title	Discovery of serum protein biomarkers of Active Tuberculosis in HIV- and HIV+ Individuals (US center)
Description	The overall goal of the project is to identify candidate biomarkers of Active infection with Mycobacterium tuberculosis (Mtb) in individuals with or without HIV. Samples were analyzed from two tuberculosis (TB) endemic countries, Brazil and South Africa (SA), as well as from the United States (US). The US site included patients that were in the early stages of Active TB, with mean symptom duration of 1.5 months. The subjects from the Brazil site had mean symptom duration of 6 months, and the SA site subjects had advanced TB. All sites also provided samples asymptomatic for TB or with Latent TB infection. The US and SA sites also had subjects with and without HIV co-infection, whereas the Brazilian subjects were all HIV-. This specific dataset corresponds to the Discovery step of the study, for the US center.
HostingRepository	PRIDE
AnnounceDate	2019-11-22
AnnouncementXML	Submission_2019-11-22_00:52:14.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Eustache Paramithiotis
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; deamidated residue
Instrument	Q-Tof Ultima

Revision	Datetime	Status	ChangeLog Entry
0	2013-10-14 07:17:47	ID requested
⏵ 1	2019-11-22 00:54:31	announced

Achkar JM, Cortes L, Croteau P, Yanofsky C, Mentinova M, Rajotte I, Schirm M, Zhou Y, Junqueira-Kipnis AP, Kasprowicz VO, Larsen M, Allard R, Hunter J, Paramithiotis E, Host Protein Biomarkers Identify Active Tuberculosis in HIV Uninfected and Co-infected Individuals. EBioMedicine, 2(9):1160-8(2015) [pubmed]

submitter keyword: Tuberculosis, Latent tuberculosis, Serum, Plasma, Biomarker discovery, Cohorts, US Center HIV

Eustache Paramithiotis
contact affiliation	Caprion Proteomics Inc., 201 President-Kennedy Ave., Montreal H2X 3Y7, Quebec, Canada
contact email	eparamithiotis@caprion.com
lab head
Eustache Paramithiotis
contact affiliation	Bioinformatic
contact email	eparamithiotis@caprion.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2011/11/PXD000517

PRIDE project URI

• PRIDE
  1. PXD000517
     1. Label: PRIDE project
     2. Name: Discovery of serum protein biomarkers of Active Tuberculosis in HIV- and HIV+ Individuals (US center)