PXD000485 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Validation dataset on tamoxifen treated Estrogen Receptor (ER) positive breast cancer patients |
Description | 56 Estrogen Receptor Positive Breast cancer tissues coming from patients treated with tamoxifen upon recurrence (41 Good outcome vs 15 Poor outcome) have been microdissected to enrich for breast cancer tumor cells. Enriched tissue has been lysed and proteins digested and analyzed in an LTQ-Orbitrap coupled online with a Dionex nLC system. Thermo output .RAW files were analyzed through MaxQuant (version 1.4.1.2) using the human proteome FASTA (version 2012-09, human canonical proteome) as search library. LFQ parameters in MaxQuant have been enabled (Fast LFQ) and other settings have been kept as default. |
HostingRepository | PRIDE |
AnnounceDate | 2015-08-21 |
AnnouncementXML | Submission_2015-08-21_02:26:11.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Tommaso De Marchi |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | iodoacetamide derivatized residue |
Instrument | LTQ Orbitrap |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2013-09-27 01:25:18 | ID requested | |
⏵ 1 | 2015-08-21 02:26:12 | announced | |
Publication List
De Marchi T, Liu NQ, Stingl C, Timmermans MA, Smid M, Look MP, Tjoa M, Braakman RB, Opdam M, Linn SC, Sweep FC, Span PN, Kliffen M, Luider TM, Foekens JA, Martens JW, Umar A, 4-protein signature predicting tamoxifen treatment outcome in recurrent breast cancer. Mol Oncol, 10(1):24-39(2016) [pubmed] |
Keyword List
submitter keyword: Mass Spectrometry, Estrogen receptor positive Breast Cancer, Tamoxifen, metastasis |
Contact List
Tommaso De Marchi |
contact affiliation | Medical Oncology |
contact email | t.demarchi@erasmusmc.nl |
lab head | |
Tommaso De Marchi |
contact affiliation | Medical Oncology |
contact email | t.demarchi@erasmusmc.nl |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2015/08/PXD000485 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD000485
- Label: PRIDE project
- Name: Validation dataset on tamoxifen treated Estrogen Receptor (ER) positive breast cancer patients