PXD000484

PXD000484 is an original dataset announced via ProteomeXchange.

Title	Discovery dataset on tamoxifen treated Estrogen Receptor (ER) positive breast cancer patients
Description	56 estrogen receptor positive breast cancer tissues from patients treated with tamoxifen upon recurrence (32 Good outcome vs 24 Poor outcome) have been microdissected to obtain a pure population of epithelial tumor cells. Breast tumor enriched tissues have been sonicated and proteins have been in-solution digested and analyzed via a LTQ-Orbitrap coupled online with a nano-LC system. Thermo output .RAW files were analyzed through MaxQuant (version 1.4.1.2) using the human proteome FASTA (version 2012-09, human canonical proteome) as search library.
HostingRepository	PRIDE
AnnounceDate	2015-08-21
AnnouncementXML	Submission_2015-08-21_01:54:42.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Tommaso De Marchi
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2013-09-26 01:51:40	ID requested
⏵ 1	2015-08-21 01:54:43	announced

De Marchi T, Liu NQ, Stingl C, Timmermans MA, Smid M, Look MP, Tjoa M, Braakman RB, Opdam M, Linn SC, Sweep FC, Span PN, Kliffen M, Luider TM, Foekens JA, Martens JW, Umar A, 4-protein signature predicting tamoxifen treatment outcome in recurrent breast cancer. Mol Oncol, 10(1):24-39(2016) [pubmed]

submitter keyword: Breast Cancer, Estrogen Receptor, shotgun proteomics

Tommaso De Marchi
contact affiliation	Medical Oncology
contact email	t.demarchi@erasmusmc.nl
lab head
Tommaso De Marchi
contact affiliation	Medical Oncology
contact email	t.demarchi@erasmusmc.nl
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2015/08/PXD000484

PRIDE project URI

• PRIDE
  1. PXD000484
     1. Label: PRIDE project
     2. Name: Discovery dataset on tamoxifen treated Estrogen Receptor (ER) positive breast cancer patients