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PXD000458

PXD000458 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleQuantitative proteomics of cryptococcal meningitis brain tissues
DescriptionQuantitative proteomics of cryptococcal meningitis brain tissues and control brain tissues was carried out to study the host factors that are activated and differentially regulated in response to infection. Proteins isolated from infected brain tissues were subjected to trypsin digestion and then labeled using 4-plex iTRAQ labels. iTRAQ labeled peptides were subjected to fractionation by SCX. All the fractions were analyzed on the high resolution Orbitrap Velos mass spectrometer.
HostingRepositoryPRIDE
AnnounceDate2015-07-24
AnnouncementXMLSubmission_2015-07-24_01:56:10.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAkhilesh Pandey
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; iTRAQ4plex-116 reporter+balance reagent acylated residue; methylthiolated residue
InstrumentLTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02013-09-11 03:06:09ID requested
12015-07-24 01:45:13announced
22015-07-24 01:56:11announcedUpdated project metadata.
Publication List
Selvan LD, Sreenivasamurthy SK, Kumar S, Yelamanchi SD, Madugundu AK, Anil AK, Renuse S, Nair BG, Gowda H, Mathur PP, Satishchandra P, Shankar SK, Mahadevan A, Keshava Prasad TS, Characterization of host response to Cryptococcus neoformans through quantitative proteomic analysis of cryptococcal meningitis co-infected with HIV. Mol Biosyst, 11(9):2529-40(2015) [pubmed]
Keyword List
curator keyword: Biomedical
submitter keyword: Human brain, cryptococcal meningitis, LTQ-Orbitrap
Contact List
Akhilesh Pandey
contact affiliationJohns Hopkins University
contact emailpandey@jhmi.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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