PXD000458 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Quantitative proteomics of cryptococcal meningitis brain tissues |
Description | Quantitative proteomics of cryptococcal meningitis brain tissues and control brain tissues was carried out to study the host factors that are activated and differentially regulated in response to infection. Proteins isolated from infected brain tissues were subjected to trypsin digestion and then labeled using 4-plex iTRAQ labels. iTRAQ labeled peptides were subjected to fractionation by SCX. All the fractions were analyzed on the high resolution Orbitrap Velos mass spectrometer. |
HostingRepository | PRIDE |
AnnounceDate | 2015-07-24 |
AnnouncementXML | Submission_2015-07-24_01:56:10.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Akhilesh Pandey |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; iTRAQ4plex-116 reporter+balance reagent acylated residue; methylthiolated residue |
Instrument | LTQ Orbitrap Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2013-09-11 03:06:09 | ID requested | |
1 | 2015-07-24 01:45:13 | announced | |
⏵ 2 | 2015-07-24 01:56:11 | announced | Updated project metadata. |
Publication List
Selvan LD, Sreenivasamurthy SK, Kumar S, Yelamanchi SD, Madugundu AK, Anil AK, Renuse S, Nair BG, Gowda H, Mathur PP, Satishchandra P, Shankar SK, Mahadevan A, Keshava Prasad TS, Characterization of host response to Cryptococcus neoformans through quantitative proteomic analysis of cryptococcal meningitis co-infected with HIV. Mol Biosyst, 11(9):2529-40(2015) [pubmed] |
Keyword List
curator keyword: Biomedical |
submitter keyword: Human brain, cryptococcal meningitis, LTQ-Orbitrap |
Contact List
Akhilesh Pandey |
contact affiliation | Johns Hopkins University |
contact email | pandey@jhmi.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2015/07/PXD000458 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD000458
- Label: PRIDE project
- Name: Quantitative proteomics of cryptococcal meningitis brain tissues