PXD000397

PXD000397 is an original dataset announced via ProteomeXchange.

Title	MDA-MB-231 Breast Cancer Bone Tropic vs Parental Hypoxic Secretome Analysis
Description	The project profiled the expression patterns in hypoxia induced secretomes between MDA-MB-231 parental and MDA-MB-231 Bone Tropic (BT) breast cancer cell lines which have been previously generated by Massague and colleagues (Kang et al. Cancer Cell 2003).
HostingRepository	PRIDE
AnnounceDate	2017-05-23
AnnouncementXML	Submission_2017-05-23_01:13:20.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Thomas Cox
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2013-08-05 02:34:05	ID requested
1	2015-05-28 01:49:04	announced
2	2015-12-17 05:45:19	announced	Updated publication reference for PubMed record(s): 26649326.
⏵ 3	2017-05-23 01:13:22	announced	Updated publication reference for PubMed record(s): 26017313, 26649326.

Cox TR, Schoof EM, Gartland A, Erler JT, Linding R, Dataset for the proteomic inventory and quantitative analysis of the breast cancer hypoxic secretome associated with osteotropism. Data Brief, 5():621-5(2015) [pubmed]

Cox TR, Rumney RMH, Schoof EM, Perryman L, H, ø, ye AM, Agrawal A, Bird D, Latif NA, Forrest H, Evans HR, Huggins ID, Lang G, Linding R, Gartland A, Erler JT, The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase. Nature, 522(7554):106-110(2015) [pubmed]

curator keyword: Biomedical

submitter keyword: Lysyl Oxidase

Breast Cancer

Hypoxia

Secretome

Pre-metastatic Niche

Bone

Janine T Erler
contact affiliation	Biotech Research and Innovation Centre (BRIC) University of Copenhagen Ole Maaløes Vej 5 2200 Copenhagen N Denmark
contact email	janine.erler@bric.ku.dk
lab head
Thomas Cox
contact affiliation	Biotech Research and Innovation Centre
contact email	coxthomasr@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2015/05/PXD000397

PRIDE project URI

• PRIDE
  1. PXD000397
     1. Label: PRIDE project
     2. Name: MDA-MB-231 Breast Cancer Bone Tropic vs Parental Hypoxic Secretome Analysis