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PXD000046

PXD000046 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMouse Cerebellum DNA-Damage 2D LC-MS/MS
DescriptionWhole mice cerebella tissue was lysed, reduced, alkylated and digested. Three time points of control and KO tissue was labeled using dimethyl isotope labeling. After combination SCX fractionation was performed followed by RP LC-MS/MS analysis using an Orbitrap Velos and top 10 HCD fragmentation.
HostingRepositoryPRIDE
AnnounceDate2015-02-17
AnnouncementXMLSubmission_2015-02-17_02:57:03.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterErik L. de Graaf
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentLTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02012-10-05 06:02:12ID requested
12014-03-05 03:32:57announced
22014-07-25 00:40:29announcedUpdated project metadata.
32015-02-17 02:57:04announcedUpdated project metadata.
Publication List
de Graaf EL, Vermeij WP, de Waard MC, Rijksen Y, van der Pluijm I, Hoogenraad CC, Hoeijmakers JH, Altelaar AF, Heck AJ, Spatio-temporal analysis of molecular determinants of neuronal degeneration in the aging mouse cerebellum. Mol Cell Proteomics, 12(5):1350-62(2013) [pubmed]
Keyword List
ProteomeXchange project tag: PRIME-XS Project
submitter keyword: Mouse, Cerebellum, DNA-damage, Aging
Contact List
Erik L. de Graaf
contact affiliationBiomolecular Mass Spectrometry and Proteomics Laboratory, Utrecht University, Utrecht, The Netherlands
contact emaile.l.degraaf@uu.nl
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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