update LabHead Dataset QC0 was acquired to elaborate the transition groups for the proteotypic peptides of 21 human proteins encoded by chromosome 18. SRM-data was acquired using the synthetic peptide mixtures under the conditions of slight sample overloading on LC column. Preliminary transition groups were extracted from the results of MRM scouting of depleted plasma and liver and organized into 5 scheduled MRM assays named A to E with least overlapping of RT-window of proteotypic peptides. Decoy transitions were generated for each assay by ADD_RANDOM algorithm of mGen.